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KMID : 0387419920030020035
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Korean Society of Oriental Neuropsychiatry
1992 Volume.3 No. 2 p.35 ~ p.48
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The Anti-Stress and Analgesic Effects of Samhwasan
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Abstract
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The present study was to carried out to investigate the anti-stress effects of Samhwasan in immobilized rats. Serum levels of catecholamine and aldosterone were measured in immobillzed rats orally receiving extracts of Samhwasan, respectively, for 1 day 7 days.
And in order to investigate the analgesic effects of Samhwasan in acetic-acid injected mice, the writhing syndrome frequency was measured.
The results obtained were summarized as follow ;
1. There were decreases of norepinephrine in rats receiving Samhwasan for 1 and 7 days respectively.
2. There were decreases of epinephrine in rats receiving Samhwasan for 1 day and 7 days respectively, and significant decreases were recognized in rats receiving Samhasan for 7 days.
3. There were significant decreases of aldosterone in rats receiving Samhwasan for 1 day and 7 days respectively.
4. There were significnat decreases of writhing syndrome frequency in mice receiving Samhwasan.
These results appeared to suggest that Samhwasan produce the anti-stress effects and effects on pain relief.
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KEYWORD
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